# Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO)

Notice 173be613d10249d8b0096c649e5203b8 (solicitation ARPA-H-SOL-24-104) from HEALTH AND HUMAN SERVICES, DEPARTMENT OF, ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H), posted 2025-06-06, responses due 2029-03-06T04:59:00.000Z. Status: open.

| Field | Value |
| --- | --- |
| Notice ID | 173be613d10249d8b0096c649e5203b8 |
| Solicitation number | ARPA-H-SOL-24-104 |
| Type | Solicitation |
| Agency | HEALTH AND HUMAN SERVICES, DEPARTMENT OF |
| Sub-tier | NATIONAL INSTITUTES OF HEALTH |
| Office | ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H) |
| Posted | 2025-06-06T13:36:47.000Z |
| Response deadline (UTC) | 2029-03-06T04:59:00.000Z |
| Set-aside | - |
| NAICS | 541715 |
| PSC | AN13 |
| Place of performance | USA |
| Award | - |

## Description

This ISO seeks solution summaries and proposal submissions for projects that fall within the general scope of the ARPA-H Health Science Futures (HSF) mission office. HSF expands what is technically possible by developing approaches that will remove the scientific and technological limitations that stymie progress towards the healthcare of the future. HSF supports cutting-edge, often disease-agnostic research programs that have the potential for translational real-world change. Solution summary submissions must be submitted to: https://solutions.arpa-h.gov Questions must be submitted to: https://solutions.arpa-h.gov/Ask-A-Question/ Proposal submission should be submitted to: https://solutions.arpa-h.gov/Submit-Proposal/ Amendment 2 is effective immediately; however, if an entity has previously submitted a solution summary and/or a proposal, the base solicitation will be followed for those submissions. If a solution summary is submitted; however, a proposal has not been submitted yet, the proposal will be evaluated in accordance with this amendment. The amendment: Updated solutions summary template; Updated bundle of attachments for other transactions (admin & national policy requirements document, cost proposal narrative, cost proposal workbook, task description document, and technical & management proposal) for proposal submissions; Removed cooperative agreements as a potential award instrument and removed bundle of attachments for cooperative agreements; Updated various sections of the ISO.

## Sources

- View on SAM.gov: https://sam.gov/opp/173be613d10249d8b0096c649e5203b8/view
- Data as of 2026-11-14. Source: https://sam.gov/data-services/Contract%20Opportunities/datagov

## Cite this

"Health Science Futures (HSF) Mission Office Innovative Solutions Opening (ISO), SAM.gov contract opportunity 173be613d10249d8b0096c649e5203b8." samgovapi.io, https://samgovapi.io/opportunity/173be613d10249d8b0096c649e5203b8, data as of 2026-11-14. Primary record: https://sam.gov/opp/173be613d10249d8b0096c649e5203b8/view

## API and MCP

- REST: GET https://samgovapi.io/api/v1/opportunities/173be613d10249d8b0096c649e5203b8
- MCP tool: get_opportunity

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