# Non-Optical Methods for High Speed Protein Control

Notice 406c91d063494363aee2746d5fe476df (solicitation DARPA-SN-26-89) from DEPT OF DEFENSE, DEF ADVANCED RESEARCH PROJECTS AGCY, posted 2026-07-21, responses due 2027-01-01T04:59:00.000Z. Status: open.

| Field | Value |
| --- | --- |
| Notice ID | 406c91d063494363aee2746d5fe476df |
| Solicitation number | DARPA-SN-26-89 |
| Type | Special Notice |
| Agency | DEPT OF DEFENSE |
| Sub-tier | DEFENSE ADVANCED RESEARCH PROJECTS AGENCY  (DARPA) |
| Office | DEF ADVANCED RESEARCH PROJECTS AGCY |
| Posted | 2026-07-21T13:07:29.000Z |
| Response deadline (UTC) | 2027-01-01T04:59:00.000Z |
| Set-aside | - |
| NAICS | 541714 |
| PSC | AC12 |
| Place of performance | - |
| Award | - |

## Description

UPDATE: The purpose of Amendment 1 to DARPA-SN-26-89, the Non-Optical Methods for High Speed Protein Control Special Notice (SN), is to clarify the notice deadline. DARPA BTO will be actively “shopping” the ERIS Marketplace for innovative, post-competitive, awardable solutions that address the need for a new class of rapidly switchable, non-optogenetic protein domains for real-time cellular control. This effort seeks to develop a robust and versatile molecular tool for massless information transfer across a cell membrane, intended to supplement existing synthetic biology platforms.

## Sources

- View on SAM.gov: https://sam.gov/opp/406c91d063494363aee2746d5fe476df/view
- Data as of 2026-11-14. Source: https://sam.gov/data-services/Contract%20Opportunities/datagov

## Cite this

"Non-Optical Methods for High Speed Protein Control, SAM.gov contract opportunity 406c91d063494363aee2746d5fe476df." samgovapi.io, https://samgovapi.io/opportunity/406c91d063494363aee2746d5fe476df, data as of 2026-11-14. Primary record: https://sam.gov/opp/406c91d063494363aee2746d5fe476df/view

## API and MCP

- REST: GET https://samgovapi.io/api/v1/opportunities/406c91d063494363aee2746d5fe476df
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